Understanding factors affecting medication treatment for opioid use disorder and overdose risk
Official title: Social and behavioral determinants of MOUD utilization and opioid overdose
Funded at University of Massachusetts Lowell · NIH-11099942 · Data updated 2026-11-12
This study looks at how things like having a stable job or home, and mental health challenges, can affect people’s ability to get and stick with medication for opioid use disorder, and it aims to find ways to make treatment more effective and safer for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Lowell NIH-funded |
| Lab location | 1 site (Lowell, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $699,591 |
| NIH project number | 5R01DA056470-03 |
| Project ID | NIH-11099942 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults, particularly veterans, who are struggling with opioid use disorder and face social or behavioral challenges.
✕Less likely to help
Patients who do not have opioid use disorder or those who are not affected by social and behavioral determinants of health may not benefit from this research.
What this research studies
This research investigates the social and behavioral factors that influence the use of medication treatment for opioid use disorder (MOUD) and the risk of opioid overdose. It focuses on understanding how conditions like job and housing insecurity, as well as mental health issues, affect access to and retention in MOUD programs. By analyzing data from various clinical settings, the study aims to identify barriers to effective treatment and develop strategies to improve patient outcomes. The research will utilize advanced data analysis techniques to uncover patterns and correlations that can inform better healthcare practices.
Why it matters
Potential benefit: If successful, this research could lead to improved access to and retention in medication treatments for opioid use disorder, ultimately reducing overdose rates.
How similar studies have gone: Previous research has shown that addressing social determinants of health can significantly improve treatment outcomes for substance use disorders, indicating a promising approach.
Where this research is happening
-
University of Massachusetts Lowell
Lowell, United States Active
Researchers
- Principal investigator: Yu, Hong — University of Massachusetts Lowell
- Study coordinator: Yu, Hong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.