Understanding factors affecting medication treatment for opioid use disorder and overdose risk

Social and behavioral determinants of MOUD utilization and opioid overdose

NIH-funded research University of Massachusetts Lowell · NIH-11099942

This study looks at how things like having a stable job or home, and mental health challenges, can affect people’s ability to get and stick with medication for opioid use disorder, and it aims to find ways to make treatment more effective and safer for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Lowell NIH-funded
Lab location1 site (Lowell, United States)
Project IDNIH-11099942 on NIH RePORTER

What this research studies

This research investigates the social and behavioral factors that influence the use of medication treatment for opioid use disorder (MOUD) and the risk of opioid overdose. It focuses on understanding how conditions like job and housing insecurity, as well as mental health issues, affect access to and retention in MOUD programs. By analyzing data from various clinical settings, the study aims to identify barriers to effective treatment and develop strategies to improve patient outcomes. The research will utilize advanced data analysis techniques to uncover patterns and correlations that can inform better healthcare practices.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults, particularly veterans, who are struggling with opioid use disorder and face social or behavioral challenges.

Not a fit: Patients who do not have opioid use disorder or those who are not affected by social and behavioral determinants of health may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved access to and retention in medication treatments for opioid use disorder, ultimately reducing overdose rates.

How similar studies have performed: Previous research has shown that addressing social determinants of health can significantly improve treatment outcomes for substance use disorders, indicating a promising approach.

Where this research is happening

Lowell, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.