Understanding Eye Muscle Mechanics for Vision Problems

Biomechanical Analysis in Strabismus Surgery

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11094886

This project explores how eye muscles and the optic nerve work to help us see, aiming to improve treatments for crossed eyes, glaucoma, and severe nearsightedness.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-11094886 on ClinicalTrials.gov

What this research studies

This research aims to understand the biomechanics of eye muscles and the optic nerve in both healthy eyes and those with visual diseases. We want to uncover new ways eye muscles maintain proper eye alignment and identify mechanical effects that might contribute to conditions like glaucoma and severe nearsightedness. By clarifying how eye movements create forces on the eye, we hope to improve treatments for strabismus (crossed eyes) and gain insights into the causes of other serious eye conditions.

Who could benefit from this research

Good fit: This foundational research does not directly recruit patients, but its findings could eventually benefit individuals with strabismus, glaucoma, or severe myopia, including both children and adults.

Not a fit: Patients without conditions related to eye muscle biomechanics, strabismus, glaucoma, or severe myopia would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to more effective surgical techniques for strabismus, better understanding and prevention of glaucoma, and new insights into the causes of severe myopia.

How similar studies have performed: This research builds upon existing knowledge of eye anatomy and biomechanics, but it proposes novel hypotheses regarding the dynamic effects of eye movements on eye health and disease.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.