Understanding everyday memory in aging and early Alzheimer's

The role of prior knowledge and event segmentation in age- and Alzheimer's-related changes in event memory

NIH-funded research Kansas State University · NIH-11135404

This project explores how our memory for daily events, like conversations or grocery trips, changes as we get older and in the early stages of Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKansas State University NIH-funded
Lab location1 site (Manhattan, United States)
Project IDNIH-11135404 on NIH RePORTER

What this research studies

We want to understand why memory for everyday activities becomes challenging for older adults and those with early Alzheimer's disease. Our approach uses realistic, continuous experiences to see how people form memories in real-time, rather than relying on artificial lab tests. We will look at how people use their existing knowledge to create stable mental pictures of events and if this ability changes with age or early Alzheimer's. This helps us learn more about how memory works in daily life.

Who could benefit from this research

Good fit: Ideal candidates for this type of research would be older adults, including those who are cognitively healthy and those in the early stages of Alzheimer's disease.

Not a fit: Patients with advanced Alzheimer's disease or individuals who are not older adults may not directly benefit from this specific research focus.

Why it matters

Potential benefit: If successful, this work could help improve older adults' ability to remember day-to-day information, make important life decisions, and interact with new technologies, ultimately enhancing their quality of life.

How similar studies have performed: This project takes a novel approach by focusing on real-world, continuous experiences, which differs from many traditional laboratory memory tests.

Where this research is happening

Manhattan, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.