Understanding epilepsy risk in very preterm infants with brain hemorrhage
Epilepsy and Neurodevelopmental Risk Stratification in Very Preterm Infants with Intraventricular Hemorrhage
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11080978
This study is looking at how very premature babies who have serious bleeding in the brain might develop epilepsy and other developmental challenges, and it aims to find early signs that could help doctors identify these risks so they can provide better care and support for these little ones.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11080978 on ClinicalTrials.gov |
What this research studies
This research investigates how very preterm infants who experience high-grade intraventricular hemorrhage (IVH) may develop epilepsy and neurodevelopmental issues. By using advanced techniques like high-density EEG to monitor brain network changes, the study aims to identify early biomarkers that can predict these outcomes. The goal is to gather data during a critical period of brain development, which could lead to better screening and intervention strategies for at-risk infants. This approach focuses on understanding the brain's connectivity to improve future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are very preterm infants (born at or before 32 weeks of gestation) who have experienced high-grade intraventricular hemorrhage.
Not a fit: Patients who are not very preterm or do not have a history of intraventricular hemorrhage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early identification and intervention strategies that significantly reduce the risk of epilepsy and improve developmental outcomes for affected infants.
How similar studies have performed: Previous research has shown promise in using brain network assessments to predict epilepsy in high-risk populations, indicating that this approach may yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRIPLETT, REGINA — WASHINGTON UNIVERSITY
- Study coordinator: TRIPLETT, REGINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury