Understanding Environmental Factors in Alzheimer's Risk

Environmental Exposome as a Driver in Alzheimer’s Disease

NIH-funded research Ut Southwestern Medical Center · NIH-11158840

This project explores how our surroundings and daily exposures might increase the risk of Alzheimer's disease in different communities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-11158840 on NIH RePORTER

What this research studies

This project looks into how the environment we live in and the things we are exposed to might play a big role in developing Alzheimer's disease. Researchers are using blood samples from 3,000 people who are already part of the Health & Aging Brain Study to understand these connections. By studying these samples, we hope to identify specific environmental factors that contribute to Alzheimer's risk. The goal is to find ways to help people in different communities reduce their exposure to these factors and potentially lower their chances of getting Alzheimer's.

Who could benefit from this research

Good fit: This research is particularly relevant for individuals concerned about environmental influences on Alzheimer's disease, especially those from diverse communities.

Not a fit: Patients who are not at risk for Alzheimer's disease or whose condition is not linked to environmental factors may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to practical ways for people to reduce their exposure to harmful environmental factors and potentially lower their risk of developing Alzheimer's disease.

How similar studies have performed: While the concept of the exposome in Alzheimer's is a growing area, previous research has highlighted the importance of various environmental factors in disease risk.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.