Understanding Energy Pathways in Cancer and Alzheimer's Disease
Chemical and Structural Approaches to Study Energy Homeostasis Pathways in Cancer and Metabolic disorders
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11145090
This research explores how our cells manage energy and proteins to find new ways to help people with conditions like cancer and Alzheimer's disease.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11145090 on ClinicalTrials.gov |
What this research studies
Our bodies constantly manage energy and proteins, a process called homeostasis, which is vital for health. When this balance is disrupted, it can contribute to serious conditions like cancer and Alzheimer's disease. This project uses advanced chemical and structural techniques to look closely at these cellular processes, including how cells clean themselves through a pathway called autophagy. By understanding these fundamental mechanisms, we hope to uncover new targets for future treatments.
Who could benefit from this research
Good fit: This foundational research is for future patients living with cancer, Alzheimer's disease, or related metabolic conditions who may benefit from new treatment approaches.
Not a fit: Patients seeking immediate clinical interventions or direct participation in a treatment trial would not directly benefit from this early-stage laboratory research.
Why it matters
Potential benefit: If successful, this work could lead to the discovery of new drug targets and strategies for treating cancer, Alzheimer's disease, and other metabolic disorders.
How similar studies have performed: This project builds on initial successes in identifying key structures and chemical tools for important metabolic enzymes, while also exploring novel aspects of these pathways.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAZARUS, MICHAEL BLOCK — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: LAZARUS, MICHAEL BLOCK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Cancers