Understanding energy changes in the right ventricle of patients with pulmonary arterial hypertension
The state of energy in the right ventricle of patients with pulmonary arterial hypertension
This study is looking at how the heart's right ventricle works in people with pulmonary arterial hypertension (PAH) using a special imaging technique that doesn't require any invasive procedures, to help doctors better understand the condition and improve care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11109407 on NIH RePORTER |
What this research studies
This research investigates how the energy state of the right ventricle (RV) changes in patients with pulmonary arterial hypertension (PAH). It utilizes advanced imaging techniques, specifically 3D echocardiographic particle image velocimetry (Echo-PIV), to assess RV hemodynamics without the need for invasive procedures like right heart catheterization. By monitoring these changes over time, the research aims to provide insights into the progression of PAH and improve patient management. The goal is to establish a non-invasive method to evaluate RV function and its relationship with clinical outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pulmonary arterial hypertension who are undergoing clinical follow-up.
Not a fit: Patients with other forms of heart disease unrelated to pulmonary arterial hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and management of pulmonary arterial hypertension, potentially enhancing patient outcomes.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for assessing cardiac function, indicating potential success for this novel approach.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Kheradvar, Arash — University of California-Irvine
- Study coordinator: Kheradvar, Arash
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.