NIH-funded research P30 center grant

Understanding energy balance and body composition in mice to address obesity

Official title: Core D - Energy Balance and Body Composition Core

Funded at University of Kentucky · NIH-10458566 · Data updated 2026-11-12

This study is looking at how diet and genetics affect weight gain in mice by measuring their food and water intake, activity levels, and body makeup, which could help us find better ways to tackle obesity and related health problems.

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Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of Kentucky
NIH-funded
Lab location1 site (Lexington, United States)
Project startAugust 1, 2018
Project endJuly 31, 2025
Funding year2022
Award (this year)$352,317
NIH project number5P30GM127211-05
Project IDNIH-10458566 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals at risk of obesity, cardiovascular diseases, diabetes, and certain cancers.

Less likely to help

Patients who are not affected by obesity or related metabolic disorders may not receive direct benefits from this research.

What this research studies

This research focuses on quantifying energy balance and body composition in mice, which is crucial for understanding obesity and its related health issues. The study utilizes advanced equipment to measure food and water intake, physical activity, and body composition in a non-invasive manner. By analyzing these parameters, researchers aim to explore the effects of diet and genetics on obesity development. The findings could help inform strategies to combat obesity and its associated diseases.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing obesity and related health conditions in humans.

How similar studies have gone: Previous research has shown success in using similar methodologies to study obesity and its health impacts, indicating a promising approach.

Where this research is happening

  • University of Kentucky
    Lexington, United States
    Active

Researchers

  • Principal investigator: Zhou, Changcheng — University of Kentucky
  • Study coordinator: Zhou, Changcheng

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.