Understanding Endometriosis with Advanced Cell Models
Microphysiological modeling of Endometriosis
This project uses advanced cell models to understand why some women get endometriosis and others don't, even with similar risk factors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11124768 on NIH RePORTER |
What this research studies
Endometriosis causes chronic pain and infertility for many women, but the exact reasons why it develops are still unclear. Researchers are using special cells, called induced pluripotent stem cells (iPSCs), taken from the blood of women with and without endometriosis. These iPSCs are then grown into different types of cells found in the uterus and immune system. By placing these cells on a tiny "endometriosis-immune chip," scientists can observe how they interact and identify genetic differences that contribute to the condition. This innovative approach helps us learn more about the underlying causes of endometriosis.
Who could benefit from this research
Good fit: This research focuses on understanding cells from women who have endometriosis and those who do not.
Not a fit: Patients whose conditions are not related to endometriosis would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of endometriosis, paving the way for new and more effective treatments.
How similar studies have performed: This project uses innovative microfluidic and stem cell technologies to explore previously uncharted aspects of endometriosis, building on existing knowledge.
Where this research is happening
Chicago, United States
- Northwestern University — Chicago, United States (Active)
Researchers
- Principal investigator: Kim, Ji-Yong Julie — Northwestern University
- Study coordinator: Kim, Ji-Yong Julie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.