Understanding Endometriosis Through Molecular Signatures
Mass Spectrometry-based Global Molecular Approaches and Computational Tools to Determine Phenotypic and Environmental Signatures of Endometriosis
This project aims to find new ways to identify endometriosis using molecular clues from your body, hoping to make diagnosis easier and less invasive.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11158752 on NIH RePORTER |
What this research studies
Endometriosis affects many women, but diagnosing it often requires surgery, which can cause delays. Our team is looking closely at the proteins in endometriosis tissue and comparing them to healthy tissue to find unique markers. We are also examining blood samples for proteins, environmental chemicals, and other molecules that might signal the presence of the disease. By combining these molecular insights with advanced computer analysis, we hope to develop new, non-surgical ways to diagnose endometriosis and understand its different forms.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be reproductive-aged women who have been diagnosed with endometriosis or are suspected of having the condition, as well as women without the disease who can serve as controls.
Not a fit: Patients who do not have or are not at risk for endometriosis would likely not directly benefit from this specific diagnostic research.
Why it matters
Potential benefit: If successful, this work could lead to a simpler, non-surgical blood test for endometriosis, allowing for earlier diagnosis and more personalized care.
How similar studies have performed: Previous findings have shown changes in tissue proteins and metabolites in women with endometriosis, suggesting that this molecular approach holds promise.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Fisher, Susan J. — University of California, San Francisco
- Study coordinator: Fisher, Susan J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.