Understanding emotional regulation and behavior in youth exposed to HIV
TERBO BRAIN Study: Trajectories of Emotional Regulation and Behavior Outcomes and related Brain Regions And Intrinsic Networks
This study is looking at how young people who were exposed to HIV before birth but aren't infected themselves handle their emotions and behavior, and it aims to understand how their brain development over two years might affect their thinking and mental health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10897169 on NIH RePORTER |
What this research studies
This research investigates how emotional regulation and behavior outcomes are affected in youth who have been exposed to HIV and antiretroviral treatments but are not infected themselves. By examining brain development and function over a two-year period, the study aims to identify the neural mechanisms that contribute to cognitive challenges and mental health issues in these young individuals. Participants will undergo various assessments, including neuroimaging and behavioral tasks, to better understand the impact of prenatal HIV exposure on their emotional and cognitive development.
Who could benefit from this research
Good fit: Ideal candidates for this research are youth aged 10-14 years who have been exposed to HIV and antiretroviral treatments but are HIV-uninfected.
Not a fit: Patients who are not within the specified age range or who have not been exposed to HIV or antiretroviral treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions and support strategies for youth affected by prenatal HIV exposure.
How similar studies have performed: Previous research has indicated disruptions in brain development among youth with similar backgrounds, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Harvard School of Public Health — Boston, United States (Active)
Researchers
- Principal investigator: Wang, Lei — Harvard School of Public Health
- Study coordinator: Wang, Lei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.