Understanding emotional processing in aging and Alzheimer's disease

Brain ERPs to Assess Emotional Function in Normal Aging and MCI/AD

NIH-funded research University of Rochester · NIH-10767239

This study is looking at how our feelings and emotions change as we get older, especially for people with Mild Cognitive Impairment or Alzheimer's disease, and it involves young adults and older adults to see how these changes happen across different ages and brain health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10767239 on NIH RePORTER

What this research studies

This research investigates how emotional processing changes as people age, particularly focusing on those with Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). By using brain Event-Related Potentials (ERPs), the study aims to explore the relationship between emotional responses and cognitive abilities in older adults. Participants will include young adults, cognitively healthy elderly individuals, and those with MCI or early-stage AD, allowing researchers to compare emotional processing across different age groups and cognitive statuses. The study seeks to clarify how emotional function is affected by aging and neurobiological changes.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults aged 21 and above, particularly those with Mild Cognitive Impairment or early-stage Alzheimer's disease.

Not a fit: Patients with severe cognitive impairments or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and interventions for emotional dysfunction in older adults, particularly those with cognitive impairments.

How similar studies have performed: Previous research has shown promising results in understanding emotional processing in aging, making this approach both relevant and potentially impactful.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.