Understanding early stages of pulmonary fibrosis in families

Preclinical Pulmonary Fibrosis, an opportune rare disease cohort

NIH-funded research University of Colorado Denver · NIH-10898872

This study is looking at how pulmonary fibrosis starts in families with a history of lung issues, aiming to find out what genes and environmental factors might play a role before serious damage happens, so if you have a family member with interstitial pneumonia, you could help us learn more about this condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10898872 on NIH RePORTER

What this research studies

This research investigates the early stages of pulmonary fibrosis, a serious lung condition, by studying families with a history of interstitial pneumonia. It aims to identify genetic and environmental factors that contribute to the disease before irreversible lung damage occurs. By analyzing a cohort of first-degree relatives of affected individuals, the study seeks to uncover the different subtypes of the disease and their progression. Patients will be monitored and assessed to gather data on their health and potential risk factors.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have a first-degree relative with interstitial pneumonia and are currently unaffected.

Not a fit: Patients without a family history of interstitial pneumonia or those already diagnosed with advanced pulmonary fibrosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and targeted prevention strategies for pulmonary fibrosis.

How similar studies have performed: Previous research has shown promise in understanding genetic and environmental interactions in similar pulmonary conditions, suggesting potential for success in this approach.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.