Understanding early-onset Alzheimer's and other types of dementia
Official title: Early-onset Alzheimer’s and other dementia: From natural history to clinical trials
Funded at Alzheimer's Association · NIH-10669554 · Data updated 2026-11-12
This study is all about understanding the special challenges faced by people diagnosed with early-onset Alzheimer's and other dementias before age 65, and it brings together patients, caregivers, and researchers to share ideas and improve care and treatment options for everyone affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Alzheimer's Association NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | April 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $44,215 |
| NIH project number | 5R13AG072859-03 |
| Project ID | NIH-10669554 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early-onset Alzheimer's disease or other dementias before the age of 65.
✕Less likely to help
Patients with late-onset Alzheimer's disease or those without a dementia diagnosis may not benefit from this research.
What this research studies
This research focuses on the unique challenges faced by individuals diagnosed with early-onset Alzheimer's disease and other dementias, which occur before the age of 65. It aims to address the differences in clinical presentations and biological factors between early-onset and late-onset dementia. The project includes an annual conference that brings together patients, caregivers, and researchers to discuss natural history and clinical trials related to early-onset dementia. By fostering collaboration and sharing knowledge, the research seeks to improve diagnosis and treatment options for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies specifically tailored for early-onset dementia patients.
How similar studies have gone: While there has been significant research on late-onset Alzheimer's, this focus on early-onset dementia is relatively novel and has not been extensively studied in large-scale clinical trials.
Where this research is happening
-
Alzheimer's Association
Chicago, United States Active
Researchers
- Principal investigator: Carrillo, Maria C — Alzheimer's Association
- Study coordinator: Carrillo, Maria C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.