Understanding early communication in children with tuberous sclerosis complex and its link to autism.

Early Communication in Tuberous Sclerosis Complex (TSC) and its Prediction of Autism

['FUNDING_OTHER'] · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · NIH-11105881

This study is looking at how babies with tuberous sclerosis complex learn to communicate and how those skills might relate to the severity of autism, by watching videos of their vocal sounds and interactions over time.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TENNESSEE HEALTH SCI CTR (nih funded)
Locations1 site (MEMPHIS, UNITED STATES)
Trial IDNIH-11105881 on ClinicalTrials.gov

What this research studies

This research investigates how early communication skills develop in infants with tuberous sclerosis complex (TSC) and how these skills may predict the severity of autism spectrum disorder (ASD). The study will analyze audio-video recordings of infants to assess their vocal development and shared attention behaviors. By tracking these developmental milestones over time, researchers aim to identify key predictors of language outcomes and ASD severity. This approach combines various measurement techniques to provide a comprehensive understanding of language development in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants aged 0-11 years diagnosed with tuberous sclerosis complex.

Not a fit: Patients who do not have tuberous sclerosis complex or are older than 11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early interventions for children with TSC and ASD, enhancing their communication skills and overall development.

How similar studies have performed: Previous research has shown promising results in understanding language development in similar populations, indicating that this approach may yield valuable insights.

Where this research is happening

MEMPHIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.