Understanding early cognitive decline in individuals with Down syndrome
Early Cognitive Decline in Down Syndrome
['FUNDING_R01'] · UNIVERSITY OF ALABAMA IN TUSCALOOSA · NIH-10881766
This study is looking at how thinking skills change in young people with Down syndrome, ages 15 to 25, over three years, to find early signs of cognitive decline that could lead to Alzheimer's disease, so we can help them sooner.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA IN TUSCALOOSA (nih funded) |
| Locations | 1 site (TUSCALOOSA, UNITED STATES) |
| Trial ID | NIH-10881766 on ClinicalTrials.gov |
What this research studies
This research investigates how cognitive decline develops in young people with Down syndrome, particularly between the ages of 15 and 25. By conducting a longitudinal study over three years, participants will undergo cognitive and behavioral assessments every 18 months to track changes in their cognitive functions. The goal is to identify early signs of cognitive decline that may indicate the onset of Alzheimer's disease, allowing for timely interventions that could slow down the progression of cognitive issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Down syndrome aged 15 to 25 years.
Not a fit: Patients outside the age range of 15 to 25 years or those without Down syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early interventions that help maintain cognitive function in individuals with Down syndrome as they age.
How similar studies have performed: Previous research has shown promising results in understanding cognitive decline in similar populations, suggesting that this approach could yield valuable insights.
Where this research is happening
TUSCALOOSA, UNITED STATES
- UNIVERSITY OF ALABAMA IN TUSCALOOSA — TUSCALOOSA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CONNERS, FRANCES A — UNIVERSITY OF ALABAMA IN TUSCALOOSA
- Study coordinator: CONNERS, FRANCES A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.