Understanding early brain development in infants with Down syndrome
A Longitudinal MRI Study Characterizing Very Early Brain Development in Infants with Down Syndrome
This study looks at how the brains of babies with Down syndrome grow during their first two years, using special imaging to see how their development compares to other babies, with the goal of finding ways to help them thrive.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10915141 on NIH RePORTER |
What this research studies
This research investigates how the brains of infants with Down syndrome develop in the first two years of life. By using advanced imaging techniques like MRI, the study aims to identify early patterns of brain development and how they differ from typically developing infants and those with other developmental disabilities. The findings could help in creating targeted therapies that improve developmental outcomes for children with Down syndrome. The research involves collaboration among several leading institutions to ensure a comprehensive approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants aged 3 to 24 months diagnosed with Down syndrome.
Not a fit: Patients who are older than 24 months or do not have a diagnosis of Down syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies that enhance cognitive and behavioral outcomes for infants with Down syndrome.
How similar studies have performed: Other research has shown success in using neuroimaging to understand brain development in infants at risk for developmental disorders, suggesting this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Marrus, Natasha — Washington University
- Study coordinator: Marrus, Natasha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.