Understanding drug resistance in Enterobacter cloacae complex bacteria
Assessing correlation between antimicrobial resistance genes and susceptibility phenotypes for Enterobacter cloacae complex isolates from the Vet-LIRN AMR monitoring program and clinical samples
This study looks at how certain bacteria that can cause serious infections, called Enterobacter cloacae complex, resist antibiotics, and it aims to help doctors find better ways to treat these infections, especially for patients who are more at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kansas State University NIH-funded |
| Lab location | 1 site (Manhattan, United States) |
| Project ID | NIH-11073677 on NIH RePORTER |
What this research studies
This research investigates the relationship between antimicrobial resistance genes and how Enterobacter cloacae complex (ECC) bacteria respond to antibiotics. By analyzing clinical samples and those from food sources, the study aims to identify patterns of resistance that could inform treatment strategies. The research focuses on understanding how these bacteria, which can cause serious infections, develop resistance and how this impacts patient care, particularly for vulnerable populations. Patients may benefit from improved knowledge of how to treat infections caused by these bacteria.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are immunocompromised or have experienced infections caused by Enterobacter cloacae complex.
Not a fit: Patients with infections caused by other types of bacteria not related to Enterobacter cloacae complex may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options for infections caused by multi-drug resistant bacteria.
How similar studies have performed: Previous research has shown success in understanding antimicrobial resistance in similar bacterial species, indicating that this approach has potential for meaningful insights.
Where this research is happening
Manhattan, United States
- Kansas State University — Manhattan, United States (Active)
Researchers
- Principal investigator: Bai, Jianfa — Kansas State University
- Study coordinator: Bai, Jianfa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.