Understanding different types of severe asthma and how they progress
Immunometabolic phenotypes in adult severe asthma and disease progression
This study is looking at different types of severe asthma to understand how they work in the body, so we can find better treatments for people with this condition. If you have severe asthma, your participation could help us learn more about your specific needs and improve care for everyone with this condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10684256 on NIH RePORTER |
What this research studies
This research investigates the various biological mechanisms behind severe asthma by conducting extensive assessments over time. It aims to identify distinct phenotypes of severe asthma patients, focusing on those with persistent type 2 inflammation and those with non-type 2 disease. By analyzing these differences, the study seeks to improve therapeutic strategies and clinical management for patients suffering from severe asthma. Participants will undergo comprehensive immunometabolic phenotyping to better understand their specific condition and treatment needs.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with severe asthma.
Not a fit: Patients with mild asthma or those who do not meet the criteria for severe asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with severe asthma.
How similar studies have performed: Previous research has shown success in identifying distinct asthma phenotypes, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Levy, Bruce D — Brigham and Women's Hospital
- Study coordinator: Levy, Bruce D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.