Understanding different types of retinal ganglion cells that process visual information
Functional subtypes of retinal ganglion cell photoreceptors
This study is looking at special cells in the eye that help send light information to the brain, and it aims to understand how different types of these cells work, which could help us learn more about how our vision affects things like sleep and mood, ultimately benefiting people’s health and well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11074052 on NIH RePORTER |
What this research studies
This research investigates the various functional subtypes of intrinsically photosensitive retinal ganglion cells (ipRGCs) in the retina, which play a crucial role in conveying visual information to the brain. By examining their location, density, and light response properties, the study aims to differentiate these subtypes based on their anatomical characteristics and the neurotransmitters they release. This could enhance our understanding of how these cells influence behaviors such as sleep, mood, and circadian rhythms. Patients may benefit from insights into how visual processing affects their overall health and well-being.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing visual processing issues or mood disorders related to circadian rhythm disruptions.
Not a fit: Patients with no retinal function or those who do not experience visual or mood-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for visual and mood disorders by targeting specific retinal cell functions.
How similar studies have performed: Previous research has shown promise in understanding retinal ganglion cell functions, suggesting that this approach could yield valuable insights.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Sivyer, Benjamin M — Oregon Health & Science University
- Study coordinator: Sivyer, Benjamin M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.