Understanding different types of pediatric acute respiratory distress syndrome and their outcomes
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome
This study is looking at how to better understand and treat a serious breathing problem in kids called pediatric ARDS by finding different types of the condition, so doctors can provide more personalized care instead of just using adult treatment guidelines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10647683 on NIH RePORTER |
What this research studies
This research investigates pediatric acute respiratory distress syndrome (ARDS), a serious condition affecting children that leads to severe breathing difficulties. The study aims to identify distinct subtypes of ARDS by analyzing biomarkers and clinical outcomes, which could help tailor treatments specifically for children rather than relying on adult guidelines. By focusing on the unique characteristics of pediatric ARDS, the research seeks to improve risk assessment and patient management in pediatric intensive care units. The approach includes gathering data from well-defined cohorts to better understand the condition's epidemiology and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 who are diagnosed with acute respiratory distress syndrome and require mechanical ventilation.
Not a fit: Patients with ARDS who are older than 21 years or those with conditions unrelated to respiratory distress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted treatments for children suffering from ARDS, potentially reducing mortality and improving recovery rates.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for ARDS in adults, but this approach in pediatric populations is relatively novel and untested.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Yehya, Nadir — Children's Hosp of Philadelphia
- Study coordinator: Yehya, Nadir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.