NIH-funded research R01 grant

Understanding different types of overactive bladder symptoms

Official title: Predicting phenotypes in benign urology

Funded at Duke University · NIH-11013904 · Data updated 2026-11-12

This study is looking at the different types of overactive bladder symptoms, like needing to go to the bathroom often or urgently, to help doctors find better treatments that work for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startFebruary 1, 2024
Project endNovember 30, 2027
Funding year2025
Award (this year)$553,096
NIH project number5R01DK138121-02
Project IDNIH-11013904 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing symptoms of overactive bladder, such as urinary urgency, frequency, and nocturia.

Less likely to help

Patients with overactive bladder symptoms that are caused by identifiable medical conditions may not benefit from this research.

What this research studies

This research investigates the various underlying subtypes of overactive bladder (OAB) symptoms, such as urinary urgency and frequency. By analyzing data from large patient cohorts, the study aims to classify these symptoms into clinically meaningful subtypes using advanced algorithms. The research will also incorporate biological data to enhance the understanding of these subtypes and their potential responses to different treatments. This approach seeks to improve targeted treatment strategies for patients experiencing OAB.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with overactive bladder.

How similar studies have gone: Previous research has shown promise in classifying urologic symptoms, indicating that this approach may yield valuable insights.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Siddiqui, Nazema Y — Duke University
  • Study coordinator: Siddiqui, Nazema Y

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.