Understanding different types of lung high blood pressure in patients with connective tissue diseases
Distinguishing Phenotypes of Pulmonary Hypertension in Patients with Connective Tissue Disease-related Interstitial Lung Disease
This study is looking at how pulmonary hypertension affects people with lung disease related to connective tissue disorders, using special imaging and tests to understand the different causes and help find better treatment options for them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10988234 on NIH RePORTER |
What this research studies
This research investigates pulmonary hypertension (PH) in patients with connective tissue disease-related interstitial lung disease (CTD-ILD). It aims to differentiate the underlying causes of PH in these patients, which can vary significantly and affect treatment options. The study will utilize advanced imaging techniques, such as computed tomography (CT), and pulmonary function tests (PFT) to assess the severity of lung damage and blood vessel function. By identifying the specific mechanisms of PH in CTD-ILD patients, the research seeks to guide more effective treatment decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with connective tissue disease-related interstitial lung disease who also experience pulmonary hypertension.
Not a fit: Patients with pulmonary hypertension not related to connective tissue diseases or those with other forms of interstitial lung disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients suffering from pulmonary hypertension related to connective tissue diseases.
How similar studies have performed: While there has been research on pulmonary hypertension in general, this specific focus on connective tissue disease-related interstitial lung disease is relatively novel and underexplored.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Khan, Sarah — Johns Hopkins University
- Study coordinator: Khan, Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.