Understanding different types of lung high blood pressure in patients with connective tissue diseases
Official title: Distinguishing Phenotypes of Pulmonary Hypertension in Patients with Connective Tissue Disease-related Interstitial Lung Disease
Funded at Johns Hopkins University · NIH-10988234 · Data updated 2026-11-12
This study is looking at how pulmonary hypertension affects people with lung disease related to connective tissue disorders, using special imaging and tests to understand the different causes and help find better treatment options for them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $90,140 |
| NIH project number | 5F32HL170482-02 |
| Project ID | NIH-10988234 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with connective tissue disease-related interstitial lung disease who also experience pulmonary hypertension.
✕Less likely to help
Patients with pulmonary hypertension not related to connective tissue diseases or those with other forms of interstitial lung disease may not benefit from this research.
What this research studies
This research investigates pulmonary hypertension (PH) in patients with connective tissue disease-related interstitial lung disease (CTD-ILD). It aims to differentiate the underlying causes of PH in these patients, which can vary significantly and affect treatment options. The study will utilize advanced imaging techniques, such as computed tomography (CT), and pulmonary function tests (PFT) to assess the severity of lung damage and blood vessel function. By identifying the specific mechanisms of PH in CTD-ILD patients, the research seeks to guide more effective treatment decisions.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients suffering from pulmonary hypertension related to connective tissue diseases.
How similar studies have gone: While there has been research on pulmonary hypertension in general, this specific focus on connective tissue disease-related interstitial lung disease is relatively novel and underexplored.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Khan, Sarah — Johns Hopkins University
- Study coordinator: Khan, Sarah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.