Understanding different types of high-grade serous ovarian cancer
Characterization of high-grade serous ovarian cancer subtypes via single-cell profiling
This study is looking at the different types of high-grade serous ovarian cancer by examining the individual cells in tumors to better understand how they work, which could help create more effective treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10836456 on NIH RePORTER |
What this research studies
This research investigates the various subtypes of high-grade serous ovarian cancer (HGSOC) by examining the cellular makeup of tumors at a single-cell level. Using advanced technologies, researchers will analyze gene expression and protein levels in individual cancer cells to uncover how these factors contribute to the characteristics of different HGSOC subtypes. The study aims to improve our understanding of tumor biology, which could lead to better-targeted therapies for patients. By deconvolving existing data from larger cohorts, the research will also explore survival outcomes based on tumor composition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with high-grade serous ovarian cancer who are seeking advanced treatment options.
Not a fit: Patients with other types of ovarian cancer or those who do not have a confirmed diagnosis of high-grade serous ovarian cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with high-grade serous ovarian cancer.
How similar studies have performed: Previous research has shown promise in using single-cell profiling to understand cancer subtypes, indicating that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Greene, Casey S — University of Colorado Denver
- Study coordinator: Greene, Casey S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.