Understanding different types of diabetes and their progression over time
Longitudinal omics-based trajectories of type 2 diabetes subtypes: the T2D Heterogeneity Consortium
['FUNDING_U01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10974745
This study is looking at different types of type 2 diabetes to find better ways to diagnose and treat it, so patients can get more personalized care that fits their unique needs.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10974745 on ClinicalTrials.gov |
What this research studies
This research investigates the various subtypes of type 2 diabetes by analyzing clinical and multi-omic data to improve diagnosis and treatment. It aims to redefine how diabetes and prediabetes are classified, moving beyond traditional glucose and HbA1c measures. By integrating diverse data types, the study seeks to develop predictive models that can track disease progression and personalize treatment strategies for better patient outcomes. Patients may benefit from more accurate diagnoses and tailored therapies that address their specific diabetes subtype.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults diagnosed with type 2 diabetes or those at risk of developing the condition.
Not a fit: Patients with type 1 diabetes or those who do not have diabetes or prediabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnoses and personalized treatment plans for individuals with type 2 diabetes.
How similar studies have performed: Previous research has shown promise in classifying diabetes subtypes using multi-omic approaches, indicating potential for success in this novel investigation.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANNING, ALISA KNODLE — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: MANNING, ALISA KNODLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus