NIH-funded research R01 grant

Understanding different types of depression in young people

Official title: Developmental pathways model of depression heterogeneity

Funded at State University New York Stony Brook · NIH-11093420 · Data updated 2026-11-12

This study is looking at how different kinds of depression develop in teens and young adults, focusing on what causes them and how they affect people over time, so if you're dealing with depression, your experiences could help us understand it better!

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University New York Stony Brook
NIH-funded
Lab location1 site (Stony Brook, United States)
Project startMay 22, 2024
Project endFebruary 29, 2028
Funding year2025
Award (this year)$674,627
NIH project number5R01MH133652-02
Project IDNIH-11093420 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents and young adults aged 14-24 who are experiencing different forms of depression.

Less likely to help

Patients who do not have depressive disorders or are outside the age range of 14-24 may not benefit from this research.

What this research studies

This research investigates how different types of depression, specifically time-limited and chronic-intermittent depression, develop in adolescents and young adults. It aims to identify the underlying causes and how these conditions affect individuals differently over time. By examining factors such as severe life stressors and reward responsiveness, the study seeks to clarify how these elements contribute to the onset and progression of depression. Participants will be part of a longitudinal study that tracks their mental health and responses to various life events.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments tailored to the specific type of depression experienced by patients.

How similar studies have gone: While research on depression is extensive, this specific approach to differentiating between subtypes based on developmental pathways is relatively novel.

Where this research is happening

  • State University New York Stony Brook
    Stony Brook, United States
    Active

Researchers

  • Principal investigator: Kotov, Roman I — State University New York Stony Brook
  • Study coordinator: Kotov, Roman I

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.