Understanding different types of blepharospasm

Deep phenotyping in blepharospasm

NIH-funded research Emory University · NIH-10932192

This study is looking into blepharospasm, a condition that causes uncontrollable blinking and eyelid spasms, to better understand the different types of it and improve how we diagnose and treat people who have it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10932192 on NIH RePORTER

What this research studies

This research investigates blepharospasm, a condition characterized by involuntary muscle contractions around the eyes leading to excessive blinking and eyelid spasms. The study aims to identify distinct subtypes of blepharospasm through advanced phenotyping techniques, which will help in understanding the different underlying mechanisms and symptoms associated with the condition. By employing cluster analyses and developing new assessment tools, the research seeks to improve diagnosis and treatment options for patients suffering from this disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with blepharospasm, particularly those experiencing varying symptoms and treatment responses.

Not a fit: Patients with blepharospasm who do not exhibit distinct subtypes or those whose symptoms are not responsive to current treatment methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment strategies for patients with blepharospasm.

How similar studies have performed: Previous research has shown success in identifying subtypes of dystonia, suggesting that this approach may yield valuable insights for blepharospasm as well.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.