Understanding different symptoms of obstructive sleep apnea
Official title: Mechanisms that Account for Different Symptom Subtypes of OSA
Funded at University of Pennsylvania · NIH-10880330 · Data updated 2026-11-12
This study is looking at the different ways obstructive sleep apnea (OSA) can affect people, especially how it makes them feel sleepy and how their bodies respond, to help find better treatments that fit each person's needs.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $250,014 |
| NIH project number | 5P01HL160471-02 |
| Project ID | NIH-10880330 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with obstructive sleep apnea who exhibit varying degrees of excessive sleepiness and other related symptoms.
✕Less likely to help
Patients without a diagnosis of obstructive sleep apnea or those who do not exhibit significant symptoms related to the condition may not benefit from this research.
What this research studies
This research investigates the various symptom subtypes of obstructive sleep apnea (OSA), focusing on how these subtypes differ in terms of excessive sleepiness and other physiological traits. By utilizing advanced electroencephalographic (EEG) metrics and analyzing genetic variations, the study aims to uncover the underlying mechanisms that contribute to these differences. Patients will be assessed for their specific symptom profiles, which may help tailor more effective treatments based on their unique physiological responses. The research seeks to enhance our understanding of how OSA affects individuals differently and the associated health risks.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment strategies for patients with obstructive sleep apnea, improving their overall health outcomes.
How similar studies have gone: Previous research has shown promise in understanding symptom subtypes of obstructive sleep apnea, but this study aims to explore novel physiological and genetic factors, making it a potentially groundbreaking approach.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Justice, Anne — University of Pennsylvania
- Study coordinator: Justice, Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.