Understanding different symptoms of obstructive sleep apnea
Mechanisms that Account for Different Symptom Subtypes of OSA
This study is looking at the different ways obstructive sleep apnea (OSA) can affect people, especially how it makes them feel sleepy and how their bodies respond, to help find better treatments that fit each person's needs.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10880330 on NIH RePORTER |
What this research studies
This research investigates the various symptom subtypes of obstructive sleep apnea (OSA), focusing on how these subtypes differ in terms of excessive sleepiness and other physiological traits. By utilizing advanced electroencephalographic (EEG) metrics and analyzing genetic variations, the study aims to uncover the underlying mechanisms that contribute to these differences. Patients will be assessed for their specific symptom profiles, which may help tailor more effective treatments based on their unique physiological responses. The research seeks to enhance our understanding of how OSA affects individuals differently and the associated health risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with obstructive sleep apnea who exhibit varying degrees of excessive sleepiness and other related symptoms.
Not a fit: Patients without a diagnosis of obstructive sleep apnea or those who do not exhibit significant symptoms related to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment strategies for patients with obstructive sleep apnea, improving their overall health outcomes.
How similar studies have performed: Previous research has shown promise in understanding symptom subtypes of obstructive sleep apnea, but this study aims to explore novel physiological and genetic factors, making it a potentially groundbreaking approach.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Justice, Anne — University of Pennsylvania
- Study coordinator: Justice, Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.