Understanding different forms of type 2 diabetes
Subtyping COre for Research on the Etiology of Type 2 Diabetes (SCORE-T2D)
['FUNDING_U01'] · UNIVERSITY OF COLORADO DENVER · NIH-11388800
This project will use clinical, genetic, behavioral, and social information to find distinct forms of type 2 diabetes that could help tailor care for adults with the condition.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11388800 on ClinicalTrials.gov |
What this research studies
If you join, researchers will collect medical measures, lab results, genetic data, behavior information, and social/environmental details from adults with type 2 diabetes. They will use modern clustering and machine‑learning methods that can handle mixed data types to find groups of people who share similar causes or treatment responses. The project emphasizes recruiting racially, ethnically, and socioeconomically diverse U.S. participants to capture patterns missed by earlier European studies. The subtyping core will develop tools and share data with other teams to support future personalized prevention and treatment efforts.
Who could benefit from this research
Good fit: Adults diagnosed with type 2 diabetes, especially those from diverse racial, ethnic, and socioeconomic backgrounds, would be ideal candidates to contribute data or samples.
Not a fit: People without type 2 diabetes or those already well controlled on established therapies are unlikely to see direct benefit from participating.
Why it matters
Potential benefit: If successful, this work could enable more personalized prevention and treatment plans for people with type 2 diabetes.
How similar studies have performed: Previous clustering analyses of large European cohorts have identified promising T2D subgroups, but these approaches are less tested in diverse U.S. populations and with mixed clinical, omics, behavioral, and social data.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KECHRIS-MAYS, KATHERINA — UNIVERSITY OF COLORADO DENVER
- Study coordinator: KECHRIS-MAYS, KATHERINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus