Understanding differences in care and outcomes for patients with gastrointestinal bleeding
Official title: Evaluation of variability in care and outcomes for patients with gastrointestinal bleeding
Funded at University of Pennsylvania · NIH-10833004 · Data updated 2026-11-12
This study is looking at how different hospitals treat patients with gastrointestinal bleeding to find ways to improve care and outcomes, so that everyone gets the best help possible no matter where they go.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | July 1, 2020 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $169,884 |
| NIH project number | 5K08DK120902-05 |
| Project ID | NIH-10833004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have been hospitalized due to gastrointestinal bleeding.
✕Less likely to help
Patients with gastrointestinal bleeding who are not hospitalized may not receive direct benefits from this research.
What this research studies
This research investigates the variability in care and outcomes for patients experiencing gastrointestinal bleeding (GIB) across different hospitals. It aims to identify modifiable factors that influence patient outcomes, such as hospital structure and processes of care, including the use of endoscopic and interventional radiology. By analyzing patient-related factors and hospital characteristics, the research seeks to develop a model that standardizes patient outcomes and improves care delivery for GIB patients. The study will also qualitatively explore additional processes of care that may affect outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved patient care and reduced mortality rates for individuals suffering from gastrointestinal bleeding.
How similar studies have gone: Other research has shown success in identifying factors that influence patient outcomes in various medical conditions, suggesting that this approach could also yield valuable insights for gastrointestinal bleeding.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Siddique, Shazia Mehmood — University of Pennsylvania
- Study coordinator: Siddique, Shazia Mehmood
Related research
Other NIH-funded projects on the same topics.
-
EpiMAX: a new injectable gel that stops GI bleeding quickly and for days
A new injectable hydrogel with epinephrine-loaded microparticles is designed to plug GI bleeds and provide immediate and lasting hemostasis for about 72 hours.
-
Sprayable hydrogel sealant to prevent gut bleeding
This project is developing a sprayable, biodegradable glue doctors could use during endoscopy to seal mucosal wounds and lower the chance of bleeding after procedures like polyp removal.
-
Using AI to improve risk assessment for patients with acute gastrointestinal bleeding
This study is working on a new tool that uses advanced technology to help doctors better understand the risk of patients having sudden stomach bleeding, so they can make smarter decisions about who needs to be hospitalized and when.
-
Direct measurement of RhD sensitization after early-pregnancy bleeding
This study tests how often Rh immunoglobulin given after bleeding in early pregnancy prevents RhD sensitization in pregnant people.
-
Dynamic risk tools to prevent blood clots and bleeding in cancer patients
A new AI-based approach will predict who among people with cancer starting treatment is at higher risk for blood clots or dangerous bleeding, helping doctors tailor preventive care.
-
Bleeding and Platelet Problems in Ehlers-Danlos Syndrome
This NIH grant looks at why people with Ehlers-Danlos syndrome bleed more and how platelet function is involved, with goals that could lead to better care during surgery or emergencies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.