Understanding diabetes risk in women with Turner syndrome
Official title: Hyperglycemia in Turner syndrome: Mechanisms and X chromosome contributions
Funded at University of Iowa · NIH-11097306 · Data updated 2026-11-12
This study is looking into why women with Turner syndrome are more likely to develop diabetes, focusing on how their genes and body work together, and it will help us learn more about their health risks related to blood sugar levels.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $162,000 |
| NIH project number | 5K23DK134810-03 |
| Project ID | NIH-11097306 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with Turner syndrome, particularly those concerned about their risk of developing diabetes.
✕Less likely to help
Patients without Turner syndrome or those who do not have concerns about diabetes may not benefit from this research.
What this research studies
This research investigates the reasons why women with Turner syndrome are at a higher risk of developing diabetes. It aims to explore the genetic and physiological mechanisms behind hyperglycemia, focusing on the role of the X chromosome. By analyzing data related to glucose tolerance and beta cell function, the study seeks to identify specific factors that contribute to diabetes in this population. Patients may undergo assessments related to their glucose levels and genetic factors to better understand their health risks.
Why it matters
Potential benefit: If successful, this research could lead to targeted prevention strategies and treatments for diabetes in women with Turner syndrome.
How similar studies have gone: While the specific mechanisms in Turner syndrome are still being explored, similar research approaches have shown promise in understanding diabetes risk in other genetic conditions.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Pinnaro, Catherina — University of Iowa
- Study coordinator: Pinnaro, Catherina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.