Understanding diabetes risk after acute pancreatitis
Official title: Diabetes RElated to Acute Pancreatitis and its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON)
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11066457 · Data updated 2026-11-12
This study is looking at how having acute pancreatitis might increase the chances of developing diabetes, and it’s for people who have experienced pancreatitis; researchers will use special devices to track blood sugar levels to learn more about this connection and help improve care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $690,764 |
| NIH project number | 5R01DK138060-02 |
| Project ID | NIH-11066457 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older who have had one or more episodes of acute pancreatitis.
✕Less likely to help
Patients who have not experienced acute pancreatitis or those under 21 years old may not benefit from this research.
What this research studies
This research investigates how acute pancreatitis can lead to diabetes by examining various mechanisms involved in this process. It aims to identify the risk factors and natural history of diabetes development following acute pancreatitis episodes. The study will utilize continuous glucose monitoring (CGM) metrics to gather detailed metabolic data from participants. By understanding these relationships, the research seeks to improve patient care and outcomes for those affected by both conditions.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and management strategies for diabetes in patients who have experienced acute pancreatitis.
How similar studies have gone: Previous research has indicated a significant link between acute pancreatitis and increased diabetes risk, suggesting that this study builds on established findings.
Where this research is happening
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Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
Related research
Other NIH-funded projects on the same topics.
-
Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.