Understanding diabetes development after acute pancreatitis
UPMC Clinical Center for the Study of Diabetes After Acute Pancreatitis
['FUNDING_U01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10894808
This study is looking at how diabetes can start quickly after a sudden inflammation of the pancreas, and it’s for people who have had acute pancreatitis; we want to understand how their insulin production changes over time and what might trigger diabetes in their case.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10894808 on ClinicalTrials.gov |
What this research studies
This research investigates how diabetes can develop quickly after an episode of acute pancreatitis by examining the loss of beta cell function. The study aims to track the progression of diabetes and the natural history of insulin sensitivity in patients who have experienced acute pancreatitis. By analyzing the role of beta cell autoimmunity, the research seeks to provide insights into the mechanisms behind diabetes onset in these patients. Participants will be closely monitored to gather comprehensive data on their condition over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals over 21 years old who have experienced an episode of acute pancreatitis.
Not a fit: Patients who have not had acute pancreatitis or those with pre-existing diabetes unrelated to pancreatitis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of diabetes that develops after acute pancreatitis.
How similar studies have performed: Other research has shown promising results in understanding diabetes mechanisms, but this specific focus on post-acute pancreatitis diabetes is relatively novel.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YADAV, DHIRAJ — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: YADAV, DHIRAJ
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.