Understanding developmental disabilities in children and teens in rural Zambia

Transdiagnostic Associations Across Developmental Disorders

NIH-funded research University of Houston · NIH-11166321

Researchers will gather health, family, brain, and genetic information from children and teens with developmental disabilities in rural Zambia to learn what causes their difficulties and what supports they need.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11166321 on NIH RePORTER

What this research studies

If my child joins, the team will enroll about 4,000 children aged 3–18 with developmental disabilities and their matched siblings in rural Zambia. Study staff will collect medical histories, developmental and behavioral assessments, brain-related measures, and genetic samples, along with information about family and community services. They will classify possible causes of the disabilities, note potential treatment options, and document what services are available and used. The project aims to link social, behavioral, brain, and genetic information to guide better care and local supports.

Who could benefit from this research

Good fit: Children aged 3–18 living in rural Zambia with developmental disabilities (for example, epilepsy, intellectual disability, or vision/hearing loss) and their siblings are the intended participants.

Not a fit: Children without developmental disabilities or those who live outside the study region or age range are unlikely to receive direct benefits from participation.

Why it matters

Potential benefit: This work could improve how causes are recognized and lead to better-targeted services and supports for children with developmental disabilities in rural Zambia.

How similar studies have performed: Related multi-level studies in other regions have helped identify causes and service gaps, but a large, comprehensive effort focused on rural Zambia is relatively novel.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.