Understanding dementia in people with Parkinson's disease

Who could benefit from this research

What this research studies

This research investigates the relationship between dementia and Parkinson's disease (PD), focusing on how cognitive decline occurs in patients over time. By examining biomarkers in cerebrospinal fluid and using advanced neuroimaging techniques, the study aims to identify changes that predict cognitive impairment in PD. Participants will be monitored through both cross-sectional and longitudinal assessments to gather comprehensive data on the progression of symptoms. The goal is to develop reliable indicators that can help in creating therapies to slow down the progression of PD-related dementia.

Why it matters

Where this research is happening

• Washington University
  Saint Louis, United States Active

Researchers

• Principal investigator: Perlmutter, Joel Synes — Washington University
• Study coordinator: Perlmutter, Joel Synes

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.