Understanding dementia in people with Parkinson's disease
Investigations of Dementia in Parkinson Disease
This study is looking at how dementia affects people with Parkinson's disease over time, and it aims to find signs that can help predict memory and thinking problems, so we can create better treatments to slow down these changes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10612119 on NIH RePORTER |
What this research studies
This research investigates the relationship between dementia and Parkinson's disease (PD), focusing on how cognitive decline occurs in patients over time. By examining biomarkers in cerebrospinal fluid and using advanced neuroimaging techniques, the study aims to identify changes that predict cognitive impairment in PD. Participants will be monitored through both cross-sectional and longitudinal assessments to gather comprehensive data on the progression of symptoms. The goal is to develop reliable indicators that can help in creating therapies to slow down the progression of PD-related dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease, particularly those experiencing cognitive decline.
Not a fit: Patients with other forms of dementia not related to Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that slow the progression of dementia in Parkinson's disease patients.
How similar studies have performed: Previous research has shown promise in using biomarkers and neuroimaging to understand dementia in other conditions, suggesting potential success for this approach in Parkinson's disease.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Perlmutter, Joel Synes — Washington University
- Study coordinator: Perlmutter, Joel Synes
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.