Understanding Dementia and Memory Changes in People Over 90

Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-Old

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11128613

This ongoing project gathers information from individuals aged 90 and older to better understand how memory and thinking abilities change with age and what causes dementia.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA AT DAVIS (nih funded)
Locations1 site (DAVIS, UNITED STATES)
Trial IDNIH-11128613 on ClinicalTrials.gov

What this research studies

Our project, called the Life After 90 Study, is collecting detailed health and lifestyle information from a diverse group of people over 90 years old. Participants have regular visits that include memory tests, health exams, and interviews about their life experiences. We also use brain imaging and look at blood samples to learn more about brain health and the causes of dementia. This helps us see the many different ways people's brains change as they get older.

Who could benefit from this research

Good fit: Ideal participants are individuals aged 90 and older from diverse backgrounds who are interested in contributing to long-term health research.

Not a fit: Patients not in the oldest-old age group or those not interested in long-term observational studies may not find direct benefit from this specific opportunity.

Why it matters

Potential benefit: This work could lead to a deeper understanding of dementia in the oldest-old, potentially guiding future strategies for prevention or treatment.

How similar studies have performed: This is a large, recently launched cohort study, building on existing knowledge but with a unique focus on the oldest-old and their diverse experiences.

Where this research is happening

DAVIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.