Understanding delayed stomach emptying and indigestion in children
Official title: Advancing Clinical Science in Pediatric Gastroparesis
Funded at Baylor College of Medicine · NIH-11158609 · Data updated 2026-11-12
This project collects health information from children and teens with delayed stomach emptying or related indigestion symptoms to create and confirm child-friendly symptom and quality-of-life questionnaires.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 25, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $346,430 |
| NIH project number | 5U01DK112194-09 |
| Project ID | NIH-11158609 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with diagnosed or suspected gastroparesis or functional dyspepsia, along with their caregivers, are the ideal candidates for this project.
✕Less likely to help
Children without digestive symptoms and adults outside the pediatric focus are unlikely to receive direct benefit from this pediatric-focused effort.
What this research studies
You would be invited to join a pediatric gastroparesis registry run by the Gastroparesis Consortium. Researchers will use interviews, caregiver input, and field testing to create and validate a PedsQL/Symptom gastroparesis module and a similar module for pediatric functional dyspepsia. Participants may complete questionnaires, provide medical history and clinical test results, and have follow-up symptom and quality-of-life tracking. The team will compare pediatric findings with adult data to identify factors linked to worse symptoms and reduced quality of life.
Why it matters
Potential benefit: If successful, this work could produce reliable child-specific symptom and quality-of-life tools that help clinicians track disease severity and tailor care for children with gastroparesis or functional dyspepsia.
How similar studies have gone: Related adult studies and prior pediatric registry efforts exist and the questionnaire approach uses established methods, but pediatric-specific validation and detailed natural history data remain limited.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Preidis, Geoffrey a — Baylor College of Medicine
- Study coordinator: Preidis, Geoffrey a
Related research
Other NIH-funded projects on the same topics.
-
New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.