Understanding decision-making issues in borderline personality disorder
Neurocomputational mechanisms of impaired social decision-making in borderline personality
This study looks at how people with borderline personality disorder (BPD) make choices in social situations, especially when those choices might lead to self-harm, and it aims to understand how their brains work during these moments to help explain why they sometimes make harmful decisions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10999871 on NIH RePORTER |
What this research studies
This research investigates how individuals with borderline personality disorder (BPD) make decisions, particularly in social situations that can lead to self-harm. It focuses on the brain's cingulo-opercular network, which is involved in goal-directed learning and may be disrupted by emotional cues. By examining the neural mechanisms behind these decision-making processes, the study aims to identify why people with BPD often make harmful choices. The research employs advanced neuroscience techniques to explore these cognitive and emotional interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with borderline personality disorder, particularly those experiencing difficulties in social decision-making.
Not a fit: Patients without a diagnosis of borderline personality disorder or those who do not exhibit decision-making impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals with borderline personality disorder, helping them make healthier decisions and reduce self-harming behaviors.
How similar studies have performed: Previous research has shown promising results in understanding decision-making processes in similar psychological conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Hallquist, Michael Nelson — Univ of North Carolina Chapel Hill
- Study coordinator: Hallquist, Michael Nelson
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.