Understanding Decision-Making in Schizophrenia
R21: Promoting Adaptive Decision-Making in Schizophrenia Through Improved Evidence Integration: A Combined Neuroimaging and Experience Sampling Study
['FUNDING_R21'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-11126717
This project looks at how people with schizophrenia make decisions, especially how they gather and use information, to help them make choices that improve their daily lives.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-11126717 on ClinicalTrials.gov |
What this research studies
People with schizophrenia often face challenges with decision-making, which can affect their daily activities and ability to pursue goals. This project aims to understand how attention, behavior, and thinking processes influence these decisions, particularly how individuals gather and integrate information before making a choice. We will use brain imaging (fMRI) and eye-tracking to observe these processes in real-time. By connecting brain signals to everyday decisions, we hope to uncover new ways to support better choices.
Who could benefit from this research
Good fit: Individuals living with schizophrenia who experience difficulties with decision-making and are willing to participate in neuroimaging and experience sampling would be ideal candidates.
Not a fit: Patients not directly participating in the imaging and experience sampling components of this foundational research may not see immediate personal benefit.
Why it matters
Potential benefit: If successful, this work could lead to new interventions that empower individuals with schizophrenia to make more adaptive decisions, potentially reducing the burden of their illness.
How similar studies have performed: While neural circuits for impaired decision-making in schizophrenia have been identified, this project explores the less-understood processes of how information is gathered and integrated before a choice, making its approach novel.
Where this research is happening
Newark, UNITED STATES
- RUTGERS BIOMEDICAL AND HEALTH SCIENCES — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZALD, DAVID HAROLD — RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- Study coordinator: ZALD, DAVID HAROLD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.