NIH-funded research R01 grant

Understanding decision-making in anorexia nervosa

Official title: Rule-Based Decision-Making: A Novel Neuroeconomic Mechanism of Anorexia Nervosa

Funded at Virginia Commonwealth University · NIH-11135363 · Data updated 2026-11-12

This study is looking at how people with anorexia nervosa make choices and why they might struggle to change their thinking or behavior, with the hope of finding better ways to help them in their recovery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University
NIH-funded
Lab location1 site (Richmond, United States)
Project startSeptember 15, 2022
Project endMay 31, 2027
Funding year2025
Award (this year)$535,502
NIH project number5R01MH126978-04
Project IDNIH-11135363 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with anorexia nervosa who exhibit cognitive and behavioral inflexibility.

Less likely to help

Patients who do not have anorexia nervosa or those with other psychiatric disorders unrelated to decision-making dysfunction may not benefit from this research.

What this research studies

This research investigates how individuals with anorexia nervosa make decisions, particularly focusing on their cognitive and behavioral inflexibility. By utilizing a novel neuroeconomic approach, the study aims to identify specific decision-making dysfunctions that contribute to the relentless pursuit of weight loss in these patients. The researchers will employ a unique task designed to probe decision processes, which may lead to more targeted and effective interventions for anorexia nervosa. The goal is to enhance our understanding of the underlying mechanisms of this disorder and improve treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatments for individuals suffering from anorexia nervosa.

How similar studies have gone: This approach is relatively novel, but prior research in decision neuroscience has shown promise in understanding other psychiatric disorders.

Where this research is happening

  • Virginia Commonwealth University
    Richmond, United States
    Active

Researchers

  • Principal investigator: Haynos, Ann Frances — Virginia Commonwealth University
  • Study coordinator: Haynos, Ann Frances

Related research

Other NIH-funded projects on the same topics.

  • Rule-Based Decision-Making in Anorexia Nervosa

    Researchers are studying how people with anorexia nervosa make decisions to understand why weight loss becomes a rigid pattern, with the aim of guiding better treatments.

    NIH research Virginia Commonwealth University · Richmond, United States · NIH-11359748

  • Rule-based decision habits in anorexia nervosa

    This project looks at whether rigid, rule-based decision habits keep people with anorexia nervosa stuck in harmful eating and behavior patterns.

    NIH research Virginia Commonwealth University · Richmond, United States · NIH-11298598

  • Understanding how avoidance affects decision-making in anorexia and bulimia

    This study is looking at how the way we learn to avoid bad experiences affects eating disorders like anorexia and bulimia, with the hope of finding better ways to help people who struggle with these issues.

    NIH research University of California, San Diego · La Jolla, United States · NIH-10996019

  • Understanding decision-making in anorexia nervosa using brain imaging techniques

    This study is looking at how young women with anorexia nervosa make decisions, especially when things are uncertain, to better understand their thought processes and help improve treatment options.

    NIH research Hofstra University · Hempstead, United States · NIH-10580198

  • Understanding how octopuses integrate sensory information and make decisions

    This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.

    NIH research Michigan State University · East Lansing, United States · NIH-9949982

  • NoviGuide for Newborn Care in Pakistan

    A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

    NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.