NIH-funded research R01 grant

Understanding decision-making in aging and Alzheimer's disease

Official title: Decision Making on Continuous Scales in Aging and Alzheimers Disease

Funded at Ohio State University · NIH-10767266 · Data updated 2026-11-12

This study is looking at how people, especially older adults and those with Alzheimer's, make quick decisions based on information they see, like finding the brightest spot on a circle, to better understand how aging and memory issues affect our choices.

More Alzheimer's Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startFebruary 1, 2020
Project endDecember 31, 2025
Funding year2024
Award (this year)$495,264
NIH project number5R01AG057841-05
Project IDNIH-10767266 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include older adults, particularly those with Mild Cognitive Impairment or early Alzheimer's disease.

Less likely to help

Patients with advanced Alzheimer's disease or severe cognitive impairments may not benefit from this research.

What this research studies

This research investigates how individuals make decisions based on information that is continuously distributed, particularly focusing on older adults and those with Alzheimer's disease. Participants will engage in tasks that require quick decisions, such as identifying the brightest area on a circle, allowing researchers to gather data on accuracy and response times. The study aims to develop a model that explains variations in decision-making across different populations, including young adults, those with Mild Cognitive Impairment, and individuals with early Alzheimer's disease. By analyzing these decision-making processes, the research seeks to uncover how aging and cognitive impairments influence our ability to make choices.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of cognitive decline in aging and Alzheimer's disease, potentially informing better therapeutic strategies.

How similar studies have gone: Previous research has shown promise in understanding decision-making processes in aging populations, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Ratcliff, Roger — Ohio State University
  • Study coordinator: Ratcliff, Roger

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.