Understanding cravings in patients receiving medication for opioid use disorder
Official title: Craving-based Digital Phenotyping During MOUD Treatment
Funded at Univ of Massachusetts Med Sch Worcester · NIH-10979126 · Data updated 2026-11-12
This study is looking at how cravings can influence the effectiveness of medications for treating opioid use disorder, and it's for people who are starting treatment with medications like buprenorphine, methadone, or naltrexone; by wearing a sensor for about two months, you'll help researchers understand how your cravings relate to your treatment success.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $797,239 |
| NIH project number | 1R01DA059640-01A1 |
| Project ID | NIH-10979126 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals initiating treatment for opioid use disorder with medications such as buprenorphine, methadone, or naltrexone.
✕Less likely to help
Patients who are not starting treatment for opioid use disorder or those not using the specified medications may not benefit from this research.
What this research studies
This research investigates how cravings affect the success of medications used to treat opioid use disorder (OUD). By using non-invasive wearable sensors, the study aims to collect data on craving patterns in patients starting treatment with medications like buprenorphine, methadone, or naltrexone. Participants will be monitored for about 60 days, allowing researchers to analyze how these cravings correlate with treatment outcomes. The goal is to develop digital profiles that can help predict how well patients respond to their treatment based on their craving data.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with opioid use disorder by tailoring interventions based on real-time craving data.
How similar studies have gone: Previous research has shown promise in using digital biomarkers to monitor health conditions, suggesting that this approach could yield valuable insights for opioid use disorder treatment.
Where this research is happening
-
Univ of Massachusetts Med Sch Worcester
Worcester, United States Active
Researchers
- Principal investigator: Carreiro, Stephanie P — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Carreiro, Stephanie P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.