Understanding cravings in patients receiving medication for opioid use disorder

Craving-based Digital Phenotyping During MOUD Treatment

NIH-funded research Univ of Massachusetts Med Sch Worcester · NIH-10979126

This study is looking at how cravings can influence the effectiveness of medications for treating opioid use disorder, and it's for people who are starting treatment with medications like buprenorphine, methadone, or naltrexone; by wearing a sensor for about two months, you'll help researchers understand how your cravings relate to your treatment success.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of Massachusetts Med Sch Worcester NIH-funded
Lab location1 site (Worcester, United States)
Project IDNIH-10979126 on NIH RePORTER

What this research studies

This research investigates how cravings affect the success of medications used to treat opioid use disorder (OUD). By using non-invasive wearable sensors, the study aims to collect data on craving patterns in patients starting treatment with medications like buprenorphine, methadone, or naltrexone. Participants will be monitored for about 60 days, allowing researchers to analyze how these cravings correlate with treatment outcomes. The goal is to develop digital profiles that can help predict how well patients respond to their treatment based on their craving data.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals initiating treatment for opioid use disorder with medications such as buprenorphine, methadone, or naltrexone.

Not a fit: Patients who are not starting treatment for opioid use disorder or those not using the specified medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with opioid use disorder by tailoring interventions based on real-time craving data.

How similar studies have performed: Previous research has shown promise in using digital biomarkers to monitor health conditions, suggesting that this approach could yield valuable insights for opioid use disorder treatment.

Where this research is happening

Worcester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.