NIH-funded research R01 grant

Understanding cravings and emotions in people with substance use disorders

Official title: SCH: Multidimensional Data Science Approach: Measuring and Characterizing Craving and Affective Profiles in Substance Use Disorders

Funded at Rice University · NIH-10896282 · Data updated 2026-11-12

This study is looking at how cravings and feelings in people with substance use issues can be better understood by using new technology, like brain scans and wearable devices, to help find the best ways to support them when they need it most.

More Substance Use Disorders research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRice University
NIH-funded
Lab location1 site (Houston, United States)
Project startAugust 1, 2023
Project endJune 30, 2027
Funding year2024
Award (this year)$299,999
NIH project number5R01DA059925-02
Project IDNIH-10896282 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with substance use disorders, including those struggling with alcohol, opioids, cocaine, or methamphetamine.

Less likely to help

Patients who do not have a substance use disorder or those who are not currently experiencing cravings may not benefit from this research.

What this research studies

This research investigates how cravings and emotional responses in individuals with substance use disorders (SUD) can be measured and characterized using advanced data science techniques. By combining laboratory measurements, such as functional MRI (fMRI), with real-world data collected through wearable sensors and mobile phones, the study aims to create a comprehensive database that captures the complex interplay between brain activity, physiological responses, and behavioral patterns. This approach seeks to identify critical moments of craving, providing opportunities for timely interventions to help individuals manage their substance use more effectively.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and treating substance use disorders by providing insights into craving triggers and emotional profiles.

How similar studies have gone: Other research has shown promise in using similar multimodal approaches to understand addiction, indicating that this methodology could yield valuable insights.

Where this research is happening

  • Rice University
    Houston, United States
    Active

Researchers

  • Principal investigator: Sano, Akane — Rice University
  • Study coordinator: Sano, Akane

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.