Understanding Craving Patterns During Opioid Use Disorder Treatment

Craving-based Digital Phenotyping During MOUD Treatment

NIH-funded research Univ of Massachusetts Med Sch Worcester · NIH-11195115

This project aims to understand how craving changes for people starting treatment for opioid use disorder by using wearable sensors and digital tools.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of Massachusetts Med Sch Worcester NIH-funded
Lab location1 site (Worcester, United States)
Project IDNIH-11195115 on NIH RePORTER

What this research studies

We are looking at how cravings change for people starting treatment for opioid use disorder, using medications like buprenorphine, methadone, or naltrexone. We will use small, wearable sensors to collect information about your body's responses over about 60 days. This information, combined with other details, helps us create a digital picture of your craving patterns. Our goal is to see if these patterns can help predict how well different treatments work for you.

Who could benefit from this research

Good fit: Ideal candidates are individuals initiating buprenorphine, methadone, or naltrexone for opioid use disorder, including those whose primary drug of choice is heroin, fentanyl, or prescription opioids.

Not a fit: Patients not currently initiating medication for opioid use disorder may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this could lead to more personalized and effective treatments for opioid use disorder by better predicting which treatments work best for individuals.

How similar studies have performed: While wearable sensors are increasingly used in health research, using them to specifically identify craving-based digital phenotypes for opioid use disorder treatment outcomes is a relatively novel approach.

Where this research is happening

Worcester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.