Understanding cranial bone growth in children with craniosynostosis
Quantitative characterization and predictive modeling of cranial bone development in patients with craniosynostosis
This study is looking at craniosynostosis, a condition in kids where the bones in their skull fuse too soon, and it aims to create a helpful computer model that can predict how their skull and brain should grow, which could lead to better ways to diagnose and treat this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10431946 on NIH RePORTER |
What this research studies
This research investigates craniosynostosis, a condition where one or more cranial sutures fuse too early, affecting brain growth and facial structure in children. The project aims to develop a personalized computational model to predict normal cranial bone development and how it is altered in craniosynostosis. By quantifying the growth patterns of cranial bones and the brain, the research seeks to provide objective tools for better diagnosis and treatment planning. This could lead to improved surgical outcomes and reduced variability in treatment approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with craniosynostosis, particularly those affected by Muenke syndrome.
Not a fit: Patients with craniosynostosis who do not have a clear diagnosis or those with other unrelated cranial conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of cranial growth, resulting in better treatment strategies for children with craniosynostosis.
How similar studies have performed: Previous research has shown promise in using computational models for predicting growth patterns in other conditions, suggesting potential success for this novel approach.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Porras Perez, Antonio Reyes — University of Colorado Denver
- Study coordinator: Porras Perez, Antonio Reyes
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.