NIH-funded research R01 grant

Understanding COVID-19's Effects on Liver Disease Patients and Telehealth Care

Official title: Impact of the COVID-19 pandemic on patient outcomes, telehealth care delivery, and treatment for unhealthy alcohol use in vulnerable patients with advanced liver disease across two healthcare systems

Funded at University of California, San Francisco · NIH-11026454 · Data updated 2026-11-12

This project looks at how the COVID-19 pandemic changed care and health for patients with advanced liver disease, especially those with alcohol-related issues, and how telehealth played a role.

More COVID-19 research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startJune 1, 2021
Project endFebruary 28, 2027
Funding year2025
Award (this year)$707,715
NIH project number5R01AA029312-05
Project IDNIH-11026454 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this type of research are patients with advanced chronic liver disease, particularly those with a history of unhealthy alcohol use, who received care during the COVID-19 pandemic.

Less likely to help

Patients without advanced liver disease or those who did not experience care disruptions or telehealth use during the COVID-19 pandemic may not directly benefit from this specific research.

What this research studies

We want to understand how the COVID-19 pandemic affected patients with advanced liver disease, particularly those who also struggle with unhealthy alcohol use. The pandemic disrupted traditional healthcare, and we are looking at how this impacted patient health and access to care. We are also examining the widespread use of telehealth during this time to see how it influenced the care these vulnerable patients received. Our goal is to learn how to better support and manage patients with advanced liver disease during public health crises and beyond.

Why it matters

Potential benefit: If successful, this work could lead to better ways to deliver care and improve health outcomes for vulnerable patients with advanced liver disease, especially during challenging times like a pandemic.

How similar studies have gone: While the specific impact of COVID-19 on this patient group and telehealth use is novel, studies on healthcare disparities and the effectiveness of alcohol cessation interventions have shown success in other contexts.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Khalili, Mandana — University of California, San Francisco
  • Study coordinator: Khalili, Mandana

Related research

Other NIH-funded projects on the same topics.

  • How high deductible health plans and COVID-19 affect access to alcohol use disorder treatment

    This study looks at how high deductible health plans and the COVID-19 pandemic affect adults' ability to get treatment for alcohol use disorder, especially for those who may already face challenges, and it aims to find ways to make care more accessible for everyone.

    NIH research Duke University · Durham, United States · NIH-10907544

  • Exploring the long-term effects of COVID-19 stress and alcohol use on older adults

    This study is looking at how the stress from the COVID-19 pandemic and drinking alcohol affects the mental and physical health of older adults, especially those who may feel more isolated or marginalized, so we can better understand their needs and find ways to help them.

    NIH research University of Florida · Gainesville, United States · NIH-10786094

  • Investigating how COVID-19 stress affects alcohol use disorders

    This study is looking at how the COVID-19 pandemic has affected people who might struggle with alcohol use, focusing on the stressors from the pandemic that could make things harder for them, and it aims to find helpful ways to support those who are at risk.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-10690037

  • Examining how the COVID-19 pandemic affected alcohol use in the U.S.

    This study is looking at how the COVID-19 pandemic has changed drinking habits and related issues for people in the U.S., especially those who might be more at risk, by asking participants about their alcohol use and mental health during and after the pandemic.

    NIH research Public Health Institute · Oakland, United States · NIH-10689923

  • How alcohol use affects COVID-19 in adolescents

    This study looks at how drinking alcohol might affect COVID-19 infection rates in teens aged 14-17, especially focusing on how it could weaken their immune systems and change their social behaviors, while also exploring how the pandemic has changed drinking habits among young people, particularly those from marginalize

    NIH research Center for Innovative Public Health Research · San Clemente, United States · NIH-10689854

  • Understanding how COVID-19 affects people with alcohol use disorder

    This study is looking at how COVID-19 and alcohol use disorder (AUD) affect each other, especially for adults who might be more at risk, and it hopes to find ways to help those who are struggling with both during the pandemic.

    NIH research Case Western Reserve University · Cleveland, United States · NIH-10687823

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.