Understanding COVID-19 disparities in African Americans through antibody testing

Supplement to U01CA260469

['FUNDING_U01'] · MICHIGAN STATE UNIVERSITY · NIH-11146976

This study is looking into why African Americans are getting COVID-19 more often and facing worse outcomes, and it aims to build trust in the community by using easy saliva tests and clear communication to encourage participation in antibody testing.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorMICHIGAN STATE UNIVERSITY (nih funded)
Locations1 site (EAST LANSING, UNITED STATES)
Trial IDNIH-11146976 on ClinicalTrials.gov

What this research studies

This research investigates the reasons behind the higher rates of COVID-19 infection and mortality among African Americans. It aims to evaluate inflammatory responses related to SARS-CoV-2 by using antibody testing to compare inflammation levels in individuals with and without confirmed infections. The study also focuses on addressing medical mistrust within the African American community by developing culturally relevant communication strategies and utilizing non-invasive salivary testing methods. By fostering trust and understanding, the research seeks to improve participation in antibody testing and ultimately reduce COVID-19 disparities.

Who could benefit from this research

Good fit: Ideal candidates for this research are African American individuals who may have been affected by COVID-19 or are interested in understanding their antibody status.

Not a fit: Patients who are not African American or those who have no interest in COVID-19 antibody testing may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for African Americans by increasing participation in COVID-19 antibody testing and addressing health disparities.

How similar studies have performed: Other research has shown success in using culturally tailored health communication strategies to improve health outcomes in minority populations, suggesting this approach may be effective.

Where this research is happening

EAST LANSING, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.