Understanding coronary artery disease using advanced CT imaging technology
Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient management
['FUNDING_R01'] · MAYO CLINIC ROCHESTER · NIH-10592395
This study is testing a new type of imaging technology to help doctors better see and understand heart artery problems in patients with coronary artery disease, especially those with tough-to-see areas, so they can avoid unnecessary procedures and keep radiation exposure low.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10592395 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the diagnosis and management of coronary artery disease (CAD) through advanced imaging techniques. It utilizes a novel photon-counting-detector dual-source CT system to provide detailed, non-invasive assessments of coronary arteries, particularly in patients with heavily calcified or stented segments that are typically difficult to evaluate. By enhancing the visualization of high-risk plaques and myocardial perfusion defects, the study aims to reduce the need for invasive procedures and lower radiation exposure for patients. The research will involve analyzing imaging data to develop algorithms that can better identify and characterize coronary atherosclerotic disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have coronary artery disease or are at risk for developing it.
Not a fit: Patients with non-coronary related cardiovascular issues or those who do not have access to the advanced imaging technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and safer diagnostic methods for coronary artery disease, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promising results with advanced imaging techniques for coronary artery disease, indicating that this approach has the potential for significant advancements in patient care.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCCOLLOUGH, CYNTHIA H — MAYO CLINIC ROCHESTER
- Study coordinator: MCCOLLOUGH, CYNTHIA H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.