Understanding coronary artery disease and its risk factors
Integrating Coronary Atherosclerosis with Physiologic Features for Optimized Risk Stratification
This study is looking at heart health by using special imaging to see how well your coronary arteries are working and to understand the buildup of plaque, especially for people who haven't had any symptoms of heart disease yet, to help figure out their risk for serious heart problems in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10805373 on NIH RePORTER |
What this research studies
This research investigates coronary artery disease (CAD) using advanced imaging techniques to assess the condition of coronary arteries and the characteristics of atherosclerotic plaques. By employing non-invasive coronary CT angiography, the study aims to evaluate various physiological features that could indicate the risk of acute coronary syndrome (ACS) and other cardiovascular events. The research will analyze both the structural and functional aspects of coronary arteries to improve risk stratification for patients, particularly those without prior symptoms of CAD. This comprehensive approach seeks to enhance the understanding of how different factors contribute to heart disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with risk factors for coronary artery disease but who have not yet been diagnosed with the condition.
Not a fit: Patients with established coronary artery disease or those already experiencing acute coronary syndrome may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to better risk assessment and prevention strategies for patients at risk of heart attacks.
How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques for assessing coronary artery disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Stone, Peter Howard — Brigham and Women's Hospital
- Study coordinator: Stone, Peter Howard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.