Understanding Colorectal Cancer Differences in Native Hawaiians

Identifying unique biological factors as potential targets to mitigate colorectal cancer health disparities in Native Hawaiians

NIH-funded research University of Hawaii at Manoa · NIH-11126746

This project aims to find unique biological factors in Native Hawaiians that contribute to colorectal cancer, hoping to discover new ways to prevent or treat the disease.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-11126746 on NIH RePORTER

What this research studies

Native Hawaiians experience higher rates of colorectal cancer, and this project seeks to understand why. Researchers are looking for specific genetic differences in Native Hawaiians that might make them more susceptible to this cancer. By studying existing biological samples and health information from a multiethnic cohort, the goal is to pinpoint unique biological factors that drive aggressive tumor development. This deeper understanding could lead to new ways to improve health outcomes for Native Hawaiians facing colorectal cancer.

Who could benefit from this research

Good fit: This research is relevant to Native Hawaiians affected by or at risk for colorectal cancer, as it focuses on ethnic-specific biological factors.

Not a fit: Patients whose colorectal cancer is not linked to the specific biological factors being studied in Native Hawaiians may not directly benefit from these particular findings.

Why it matters

Potential benefit: If successful, this work could identify new targets for therapies or prevention strategies specifically tailored to Native Hawaiians, potentially reducing colorectal cancer disparities.

How similar studies have performed: While the specific ethnic focus is unique, similar genetic and biological factor identification approaches have shown success in understanding other cancer types.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer EtiologyCancersCandidate Disease Gene
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.